Chase Budinger also scored 15 for the Timberwolves, who started the game on a 12-1 run and never trailed.
The Timberwolves (4-2) opened the third quarter on a 10-0 run to build a 16-point lead. Milwaukee cut it to nine points twice early in the fourth, but Minnesota went up by as many as 23 later in the quarter.
Rookie Jabari Parker led Milwaukee with 18 points, including 12 in the second quarter. Nate Wolters added 14 for the Bucks, who closed out their preseason schedule with a 3-4 record.
Wednesday's game was the second matchup in less than a week between Minnesota and Miwaukee. The Bucks defeated the Timberwolves 105-98 on Friday in Cedar Rapids, Iowa, which was a home game for Minnesota.
The Bucks: Point guard Brandon Knight returned to the lineup after missing the previous three games with a right groin injury. He had one point. ... Ersan Ilyasova, who missed two games with a strained right knee, also saw action, tallying 11 points and five rebounds. ... Zaza Pachulia didn't play due to a sore left hamstring. Larry Sanders remained sidelined after undergoing an unspecified outpatient medical procedure.
The Timberwolves: Five players sat out, including Andrew Wiggins, the No. 1 overall pick in the 2014 draft. Coach Flip Saunders said Wiggins hit his head on the court and bruised his backside in Sunday's game against Oklahoma City. "We're trying to be cautious," Saunders said. ... Corey Brewer, Kevin Martin, Ronny Turiaf and Mo Williams also did not play.
Milwaukee travels to Charlotte to open the regular season Oct. 29.
Minnesota closes out the preseason against the Chicago Bulls on Friday in St. Louis.
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