Aguero's clinical performance for the English champion could have been even better as he missed a penalty in the first half, but four goals were enough for him to take first place.
"Sergio AgÃ¼ero is not Lionel Messi, nor Cristiano Ronaldo, but he can be the key man in the Premier League," Ubiratan Leal of trivela.com in Brazil said. "The Argentine has the talent to raise City's level. Saturday's game was an example of it."
Ronaldo was second after finding the net twice during Real Madrid's 5-0 thrashing of Levante, with the result giving Madrid team of the week honors. Ronaldo's double took him to a Spanish league record of 15 goals in eight matches.
"Madrid manager Carlo Ancelotti said, 'Having Cristiano Ronaldo is like starting every game 1-0 up,' and the Portuguese is proving him right," Aurelio Capaldi of RAI Sport in Italy said. "Ronaldo ... has now got another record, as nobody had ever scored 15 goals after eight La Liga games."
Messi was third after scoring in Barcelona's 3-0 victory over Eibar, taking it to seven league wins in eight matches.
According to voter Sam Tighe of the Bleacher Report in England, Lahm's performance was another reminder of what World Cup winner Germany has lost. Lahm retired from internationals after the tournament in Brazil, and Germany has one win from four since his departure.
"After a week of Germany struggles in international football, Lahm's performance stood as a sour reminder of how much his presence is missed," Tighe said.
City's Aguero-inspired victory over Tottenham saw them take third, with fellow Premier League club Southampton entering the poll in fourth after a remarkable 8-0 win over Sunderland.
Pelle and Tadic arrived in the summer amid a flurry of player exits from the club, but they have both settled quickly, becoming instrumental performers as Ronald Koeman's side have risen to third.
"Winning easily against a team as poor as this Sunderland may not be a strong achievement," Cedric Rouquette of Eurosport in France said. "But an eight-goal margin is nevertheless so rare in great championships. It's the sign of a team on fire, as offensive as possible. And it's the signature of an incredible beginning to the season."
Barcelona was fifth, with Chelsea sixth after beating Crystal Palace 2-1 on Saturday. Cesc Fabregas scored the decisive goal for Chelsea and polled eighth.
Elsewhere, Marseille was seventh for its relentless start to the French league, a 2-0 win over Toulouse maintaining its seven-point lead over champion Paris Saint-Germain.
AP Global Football 10:
Real Madrid, 131 points.
Bayern Munich, 114.
Manchester City, 107.
Borussia Moenchengladbach, 50.
Deportivo La Coruna, 36.
Sergio Aguero, 154.
Cristiano Ronaldo, 134.
Lionel Messi, 88.
Philipp Lahm, 75.
Dusan Tadic, 69.
Graziano Pelle, 51.
Keisuke Honda, 50.
Cesc Fabregas, 37.
Mario Goetze, 34.
Wesley Sneijder, 23.
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