If the Chargers (9-6) win at Kansas City this weekend, they'll advance to the playoffs for the second straight season. But it's likely San Diego will face the Chiefs (8-7) without Mathews. He hasn't played or practiced since injuring his ankle against the Patriots on Dec. 7.
Center Chris Watt, who left Saturday's win over the 49ers with an ankle injury, also didn't work.
Quarterback Philip Rivers, who's been bothered by back and chest ailments, practiced for the second consecutive day.
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