HOUSTON — It all fell apart for Oakland starter Jesse Chavez in a very brief span.
"To sum up the whole day, it was three pitches and one walk," Chavez said. "That can't happen when you have the lead, and it's something that has been my Achilles heel, giving back the runs they get for me and not being able to get through six (innings)."
Chavez, who had given up five runs over his last 17 1-3 innings, spanning three starts, allowed a season-high six runs and five hits with five strikeouts in 5 1-3 innings. Chavez had allowed three home runs in his last 11 starts combined.
Carter hit a monstrous three-run shot to center field in the third to give the Astros a lead, and Castro and Krauss went back-to-back in the sixth, with Castro's homer a two-run shot.
Krauss' homer found the upper deck in right field and chased Chavez (8-7).
"You have to pitch to the park, you can't let it affect you, but I think that is what it did today," Chavez said. "It got me in trouble a little bit and it led to the walks."
Two batters later, Dominguez sent a drive onto the railroad tracks in left field off reliever Dan Otero.
The last time Houston hit three home runs in an inning was June 5, 2013, against Baltimore.
"I thought (Chavez) was throwing the ball really well, real similar to how he did last time out," A's manager Bob Melvin said. "I think the Carter at-bat affected the way things went from there."
Houston starter Brett Oberholtzer (3-7) won for the first time since May 30, giving up three runs on eight hits with two strikeouts in 6 2-3 innings.
Athletics: Right-hander Jeff Samardzija, who is 2-1 with a 2.70 ERA in four starts since being acquired July 5 from the Cubs, will start Tuesday against the Astros in the second game of the three-game series.
Astros: Right-hander Scott Feldman, who is 4-8 with a 4.60 ERA, will try to bounce back Tuesday after one of his worst starts of the season, giving up six runs in 5 1-3 innings in a 13-1 loss at Oakland Thursday.
Athletics: Outfielder Craig Gentry was placed on the 15-day disabled list Monday with a broken right hand, and the A's promoted OF Billy Burns from Double-A Midland. Gentry was injured Sunday at Texas after being hit by a pitch.
Astros: Right-hander Josh Zeid, who is on the disabled list with swelling near the left big toe, is going to see a specialist Tuesday and hopes to avoid surgery.
REDDICK SHOWS OFF GLOVE
Josh Reddick flashed the leather twice in the seventh. Enrique Hernandez led off with a sharp liner to right, but Reddick ran it down in the corner, keeping the ball from hitting the top of the fence. Jose Altuve followed with another hard-hit ball that was about to fall in. Reddick dove forward to make another highlight-reel play.
ALTUVE IS STREAKING
Houston second baseman Altuve extended his hit streak to 10 games with a single in the third inning. Altuve, who leads the Majors with 149 hits, had a season-high hitting streak of 12 games from May 8-21.