Minnesota was without regulars Seimone Augustus (left foot), Maya Moore (rest) and Lindsay Whalen (right Achilles tendon), all of whom did not travel with theÂ LynxÂ with their playoff spot as the West's top seed already secured for the fourth time in the past five seasons.
Jewell Loyd scored 14 points, Angel Goodrich had 11 and Markeisha Gatling added 10 points with 10 rebounds for Seattle (10-23).
Sylvia Fowles led Minnesota (22-12) with 21 points and 12 rebounds. Renee Montgomery had 13 points, and Asjha Jones added 11.
Seattle led 39-33 at the break, and scored the last eight points of the third to push the lead to 12.