DETROIT — Brian Dozier’s two-run single highlighted a four-run second inning, and the Minnesota Twins handed the Detroit Tigers a crucial loss by beating them 5-1 on Thursday.

The Tigers split four games with lowly Minnesota, hurting them in the crowded AL wild-card race. Detroit came into the series with a 10-2 record against the Twins.

Hector Santiago (12-8) got the win, holding the Tigers to one run in 5 2/3 innings.

Mike Pelfrey (4-10) lost in his first major league appearance since July 31. He started the game with a 60-pitch limit but lasted only 36, giving up four runs and five hits in 1 2/3 innings.

WHITE SOX 2, INDIANS 1

CHICAGO — Jose Abreu extended his hitting tear with a home run and a single, and Carlos Sanchez singled home the winning run in the ninth inning to lift Chicago over Cleveland.

The White Sox took three of four games in the series to conclude a 6-4 homestand against three playoff hopefuls. The first-place Indians remained six games ahead of Detroit in the AL Central.

David Robertson (5-3) pitched a scoreless inning for the win. Chicago starter James Shields gave up one run and three hits in six innings but remained winless in his last nine starts. He was 0-5 with a 10.75 ERA in his previous eight appearances.

Bryan Shaw (2-5) took the loss.